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Our previous work and others have shown that amino acid biosynthesis and uptake directly impact virulence and may be relevant as drug targets 13,14,15,16,17,18,19,20,21

Elliott BM & Ashby J (1980) Ethylene dibromide and disulfiram: Studies in vivo and in vitro on the mechanism of the observed synergistic carcinogenic response

Additionally, ROS production was not significantly affected by the dietary treatment, which demonstrated that the short-term mild dietary ketosis did not exhibit cytotoxic effects and had no effect on OS [Valenzano et al ., 2019]

In the pathology department, the samples were freshly dissected and snap-frozen in liquid nitrogen before storing at 80 C